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Project Group B: metabolic and systemic effectors

Project group B addresses relevant metabolic effector mechanisms and systemic crosstalk after AMI in an attempt to understand AMI as a systemic disease. To achieve this, the CRC 1116 focuses on type 2 diabetes mellitus (T2DM) and associated metabolic disorders such as non-alcoholic fatty liver, insulin resistance, prediabetes as well as effects of visceral and epicardiac adipose tissue. In addition to metabolic effector mechanisms, the contribution of immune mechanisms, clinical relevant comorbidities, such as anemia and mechanisms of remote cardiac conditioning will be analyzed.

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